Scientists Map Breast Cancer Genomes More Efficiently

Posted on December 30, 2009 in Health & Medicine, Technology

Within the next five years, scientists aim to map the genomes of 1,500 different breast cancers. Although genome mapping can be expensive and time-consuming, a new technique could help meet the deadline.

The technique, called massively parallel sequencing, causes millions of sequencing reactions to occur at the same time. Better yet, the process—which normally costs tens of thousands of dollars—can be completed for a fraction of the usual cost. The more breast cancer genomes mapped, the better idea scientists have of what causes the disease.

The genomes of 24 breast cancer tumors were mapped in the journal Nature on Dec. 23. A comparison of the tumors showed several distinct patterns of DNA damage, which indicates different sub-types of cancer. The information could help doctors develop more accurate forms of prognosis and treatment.