Popular Weight Loss Drugs Under Investigation

The Food and Drug Administration has opened an investigation on two popular weight loss drugs: Alli and Xenical. Alli is the only over the counter weight loss drug approved by the FDA. Xenical is a prescription-strength version of the drug with twice the potency. Both drugs facilitate weight loss by inhibiting the intestine’s ability to absorb fat.

Xenical was first approved by the FDA in 1999. Since that time the agency has received 32 reports of serious liver damage that may be linked to Orlistat, the active ingredient in both Xenical and Alli. Since over 11 million patients have taken Orlistat in that time, liver damage appears to be a rare side effect.

The FDA has not issued a warning to patients taking Alli or Xenical, both products of GlaxoSmithKline. Patients are to continue following their doctor’s instructions regarding the drugs, which are usually taken three times a day with meals. However patients are advised to see a doctor immediately if they notice any signs of liver damage including weakness, fever, nausea, vomiting, or jaundice.

AUTHOR: Kristina Canizares